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Extracellular Matrix Regulates Apoptosis in Mammary Epithelium through a Control on Insulin Signaling

Adherent epithelial cells require interactions with the extracellular matrix for their survival, though the mechanism is ill-defined. In long term cultures of primary mammary epithelial cells, a laminin-rich basement membrane (BM) but not collagen I suppresses apoptosis, indicating that adhesion sur...

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Detalles Bibliográficos
Autores principales: Farrelly, Nadia, Lee, Yi-Ju, Oliver, Janine, Dive, Caroline, Streuli, Charles H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150575/
https://www.ncbi.nlm.nih.gov/pubmed/10087274