Loss of Calpain 3 Proteolytic Activity Leads to Muscular Dystrophy and to Apoptosis-Associated Iκbα/Nuclear Factor κb Pathway Perturbation in Mice

Calpain 3 is known as the skeletal muscle–specific member of the calpains, a family of intracellular nonlysosomal cysteine proteases. It was previously shown that defects in the human calpain 3 gene are responsible for limb girdle muscular dystrophy type 2A (LGMD2A), an inherited disease affecting p...

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Detalles Bibliográficos
Autores principales: Richard, Isabelle, Roudaut, Carinne, Marchand, Sylvie, Baghdiguian, Stephen, Herasse, Muriel, Stockholm, Daniel, Ono, Yasuko, Suel, Laurence, Bourg, Nathalie, Sorimachi, Hiroyuki, Lefranc, Gérard, Fardeau, Michel, Sébille, Alain, Beckmann, Jacques S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150676/
https://www.ncbi.nlm.nih.gov/pubmed/11134085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150676/
https://www.ncbi.nlm.nih.gov/pubmed/11134085

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