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Absence of α-Syntrophin Leads to Structurally Aberrant Neuromuscular Synapses Deficient in Utrophin

The syntrophins are a family of structurally related proteins that contain multiple protein interaction motifs. Syntrophins associate directly with dystrophin, the product of the Duchenne muscular dystrophy locus, and its homologues. We have generated α-syntrophin null mice by targeted gene disrupti...

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Detalles Bibliográficos
Autores principales: Adams, Marvin E., Kramarcy, Neal, Krall, Stuart P., Rossi, Susana G., Rotundo, Richard L., Sealock, Robert, Froehner, Stanley C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150701/
https://www.ncbi.nlm.nih.gov/pubmed/10995443