Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling

The β-catenin signaling pathway is deregulated in nearly all colon cancers. Nonhypercalcemic vitamin D3 (1α,25-dehydroxyvitamin D(3)) analogues are candidate drugs to treat this neoplasia. We show that these compounds promote the differentiation of human colon carcinoma SW480 cells expressing vitami...

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Detalles Bibliográficos
Autores principales: Pálmer, Héctor G., González-Sancho, José Manuel, Espada, Jesús, Berciano, María T., Puig, Isabel, Baulida, Josep, Quintanilla, Miguel, Cano, Amparo, de Herreros, Antonio García, Lafarga, Miguel, Muñoz, Alberto
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150773/
https://www.ncbi.nlm.nih.gov/pubmed/11470825
http://dx.doi.org/10.1083/jcb.200102028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150773/
https://www.ncbi.nlm.nih.gov/pubmed/11470825
http://dx.doi.org/10.1083/jcb.200102028

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