Dense core secretory vesicles revealed as a dynamic Ca(2+) store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera

The role of dense core secretory vesicles in the control of cytosolic-free Ca(2+) concentrations ([Ca(2+)](c)) in neuronal and neuroendocrine cells is enigmatic. By constructing a vesicle-associated membrane protein 2–synaptobrevin.aequorin chimera, we show that in clonal pancreatic islet β-cells: (...

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Detalles Bibliográficos
Autores principales: Mitchell, Kathryn J., Pinton, Paolo, Varadi, Aniko, Tacchetti, Carlo, Ainscow, Edward K., Pozzan, Tullio, Rizzuto, Rosario, Rutter, Guy A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150797/
https://www.ncbi.nlm.nih.gov/pubmed/11571310
http://dx.doi.org/10.1083/jcb.200103145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150797/
https://www.ncbi.nlm.nih.gov/pubmed/11571310
http://dx.doi.org/10.1083/jcb.200103145

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