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Suppression of p53 function in normal human mammary epithelial cells increases sensitivity to extracellular matrix–induced apoptosis

Little is known about the fate of normal human mammary epithelial cells (HMECs) that lose p53 function in the context of extracellular matrix (ECM)–derived growth and polarity signals. Retrovirally mediated expression of human papillomavirus type 16 (HPV-16) E6 and antisense oligodeoxynucleotides (O...

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Detalles Bibliográficos
Autores principales: Seewaldt, Victoria L., Mrózek, Krzysztof, Sigle, Randy, Dietze, Eric C., Heine, Kevin, Hockenbery, David M., Hobbs, Katherine B., Caldwell, L. Elizabeth
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150841/
https://www.ncbi.nlm.nih.gov/pubmed/11673474
http://dx.doi.org/10.1083/jcb.200011001