A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast

During apoptosis, proapoptotic factors are released from mitochondria by as yet undefined mechanisms. Patch-clamping of mitochondria and proteoliposomes formed from mitochondrial outer membranes of mammalian (FL5.12) cells has uncovered a novel ion channel whose activity correlates with onset of apo...

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Detalles Bibliográficos
Autores principales: Pavlov, Evgeny V., Priault, Muriel, Pietkiewicz, Dawn, Cheng, Emily H.-Y., Antonsson, Bruno, Manon, Stephen, Korsmeyer, Stanley J., Mannella, Carmen A., Kinnally, Kathleen W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150879/
https://www.ncbi.nlm.nih.gov/pubmed/11724814
http://dx.doi.org/10.1083/jcb.200107057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150879/
https://www.ncbi.nlm.nih.gov/pubmed/11724814
http://dx.doi.org/10.1083/jcb.200107057

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