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A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast
During apoptosis, proapoptotic factors are released from mitochondria by as yet undefined mechanisms. Patch-clamping of mitochondria and proteoliposomes formed from mitochondrial outer membranes of mammalian (FL5.12) cells has uncovered a novel ion channel whose activity correlates with onset of apo...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150879/ https://www.ncbi.nlm.nih.gov/pubmed/11724814 http://dx.doi.org/10.1083/jcb.200107057 |