BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations

The breast cancer susceptibility gene BRCA1 encodes a protein that has been implicated in multiple nuclear functions, including transcription and DNA repair. The multifunctional nature of BRCA1 has raised the possibility that the polypeptide may regulate various nuclear processes via a common underl...

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Detalles Bibliográficos
Autores principales: Ye, Qinong, Hu, Yan-Fen, Zhong, Hongjun, Nye, Anne C., Belmont, Andrew S., Li, Rong
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150890/
https://www.ncbi.nlm.nih.gov/pubmed/11739404
http://dx.doi.org/10.1083/jcb.200108049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150890/
https://www.ncbi.nlm.nih.gov/pubmed/11739404
http://dx.doi.org/10.1083/jcb.200108049

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