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BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations
The breast cancer susceptibility gene BRCA1 encodes a protein that has been implicated in multiple nuclear functions, including transcription and DNA repair. The multifunctional nature of BRCA1 has raised the possibility that the polypeptide may regulate various nuclear processes via a common underl...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150890/ https://www.ncbi.nlm.nih.gov/pubmed/11739404 http://dx.doi.org/10.1083/jcb.200108049 |