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Noncanonical Wnt signaling promotes apoptosis in thymocyte development
The Wnt–β-catenin signaling pathway has been shown to govern T cell development by regulating the growth and survival of progenitor T cells and immature thymocytes. We explore the role of noncanonical, Wnt–Ca(2+) signaling in fetal T cell development by analyzing mice deficient for Wnt5a. Our findin...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150967/ https://www.ncbi.nlm.nih.gov/pubmed/18070933 http://dx.doi.org/10.1084/jem.20062692 |