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Noncanonical Wnt signaling promotes apoptosis in thymocyte development

The Wnt–β-catenin signaling pathway has been shown to govern T cell development by regulating the growth and survival of progenitor T cells and immature thymocytes. We explore the role of noncanonical, Wnt–Ca(2+) signaling in fetal T cell development by analyzing mice deficient for Wnt5a. Our findin...

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Detalles Bibliográficos
Autores principales:	Liang, Huiling, Coles, Andrew H., Zhu, Zhiqing, Zayas, Jennifer, Jurecic, Roland, Kang, Joonsoo, Jones, Stephen N.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150967/ https://www.ncbi.nlm.nih.gov/pubmed/18070933 http://dx.doi.org/10.1084/jem.20062692

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