Multiple, conserved cryptic recombination signals in V(H) gene segments: detection of cleavage products only in pro–B cells

Receptor editing is believed to play the major role in purging newly formed B cell compartments of autoreactivity by the induction of secondary V(D)J rearrangements. In the process of immunoglobulin heavy (H) chain editing, these secondary rearrangements are mediated by direct V(H)-to-J(H) joining o...

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Detalles Bibliográficos
Autores principales: Davila, Marco, Liu, Feifei, Cowell, Lindsay G., Lieberman, Anne E., Heikamp, Emily, Patel, Anjali, Kelsoe, Garnett
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150985/
https://www.ncbi.nlm.nih.gov/pubmed/18056287
http://dx.doi.org/10.1084/jem.20071224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150985/
https://www.ncbi.nlm.nih.gov/pubmed/18056287
http://dx.doi.org/10.1084/jem.20071224

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