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Multiple, conserved cryptic recombination signals in V(H) gene segments: detection of cleavage products only in pro–B cells
Receptor editing is believed to play the major role in purging newly formed B cell compartments of autoreactivity by the induction of secondary V(D)J rearrangements. In the process of immunoglobulin heavy (H) chain editing, these secondary rearrangements are mediated by direct V(H)-to-J(H) joining o...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150985/ https://www.ncbi.nlm.nih.gov/pubmed/18056287 http://dx.doi.org/10.1084/jem.20071224 |