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Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome

Pseudomonas aeruginosa is a Gram-negative bacterium that causes opportunistic infections in immunocompromised individuals. P. aeruginosa employs a type III secretion system to inject effector molecules into the cytoplasm of the host cell. This interaction with the host cell leads to inflammatory res...

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Detalles Bibliográficos
Autores principales: Sutterwala, Fayyaz S., Mijares, Lilia A., Li, Li, Ogura, Yasunori, Kazmierczak, Barbara I., Flavell, Richard A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150987/
https://www.ncbi.nlm.nih.gov/pubmed/18070936
http://dx.doi.org/10.1084/jem.20071239