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The dermis contains langerin(+) dendritic cells that develop and function independently of epidermal Langerhans cells

Langerhans cells (LCs) constitute a subset of dendritic cells (DCs) that express the lectin langerin and that reside in their immature state in epidermis. Paradoxically, in mice permitting diphtheria toxin (DT)–mediated ablation of LCs, epidermal LCs reappeared with kinetics that lagged behind that...

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Detalles Bibliográficos
Autores principales: Poulin, Lionel Franz, Henri, Sandrine, de Bovis, Béatrice, Devilard, Elisabeth, Kissenpfennig, Adrien, Malissen, Bernard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150992/
https://www.ncbi.nlm.nih.gov/pubmed/18086861
http://dx.doi.org/10.1084/jem.20071724