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The dermis contains langerin(+) dendritic cells that develop and function independently of epidermal Langerhans cells
Langerhans cells (LCs) constitute a subset of dendritic cells (DCs) that express the lectin langerin and that reside in their immature state in epidermis. Paradoxically, in mice permitting diphtheria toxin (DT)–mediated ablation of LCs, epidermal LCs reappeared with kinetics that lagged behind that...
Autores principales: | Poulin, Lionel Franz, Henri, Sandrine, de Bovis, Béatrice, Devilard, Elisabeth, Kissenpfennig, Adrien, Malissen, Bernard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150992/ https://www.ncbi.nlm.nih.gov/pubmed/18086861 http://dx.doi.org/10.1084/jem.20071724 |
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