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The enantiospecific synthesis of (+)-monomorine I using a 5-endo-trig cyclisation strategy
We have developed a general strategy for the synthesis of 2,5-syn disubstituted pyrrolidines that is based on the multi-faceted reactivity of the sulfone moiety and a 5-endo-trig cyclisation. This methodology was applied to the synthesis of indolizidine alkaloid monomorine I. Two factors were key to...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151076/ https://www.ncbi.nlm.nih.gov/pubmed/17996034 http://dx.doi.org/10.1186/1860-5397-3-39 |