Genome-Wide Expression Analysis of a Spinal Muscular Atrophy Model: Towards Discovery of New Drug Targets

Spinal Muscular Atrophy is a recessive genetic disease and affects lower motor neurones and muscle tissue. A single gene is disrupted in SMA: SMN1 activity is abolished but a second copy of the gene (SMN2) provides limited activity. While the SMN protein has been shown to function in the assembly of...

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Detalles Bibliográficos
Autores principales: Lee, Sheena, Sayin, Arzu, Grice, Stuart, Burdett, Howard, Baban, Dilair, van den Heuvel, Marcel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151137/
https://www.ncbi.nlm.nih.gov/pubmed/18167563
http://dx.doi.org/10.1371/journal.pone.0001404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151137/
https://www.ncbi.nlm.nih.gov/pubmed/18167563
http://dx.doi.org/10.1371/journal.pone.0001404

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