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Stochastic modelling of tumorigenesis in p53 deficient mice.

Stochastic models of tumorigenesis have been developed to investigate the implications of experimental data on tumour induction in wild-type and p53-deficient mice for tumorigenesis mechanisms. Conventional multistage models in which inactivation of each p53 allele represents a distinct stage predic...

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Detalles Bibliográficos
Autores principales: Mao, J. H., Lindsay, K. A., Balmain, A., Wheldon, T. E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151221/
https://www.ncbi.nlm.nih.gov/pubmed/9460995