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Biodistribution of a radiolabelled monoclonal antibody NY3D11 recognizing the neural cell adhesion molecule in tumour xenografts and patients with small-cell lung cancer.

The neural cell adhesion molecule (NCAM) is highly expressed on the surface of small-cell-lung cancer (SCLC) cells. We have produced a monoclonal antibody, NY3D11, that binds to NCAM to investigate whether this antigen could be used to develop antibody-directed therapy for SCLC. 125I-labelled IgG an...

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Detalles Bibliográficos
Autores principales: Ornadel, D., Ledermann, J. A., Eagle, K., Pedley, R. B., Boxer, G., Ward, S. E., Olabiran, Y., Bomanji, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151251/
https://www.ncbi.nlm.nih.gov/pubmed/9459153