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Detection of TP53 mutation, loss of heterozygosity and DNA content in fine-needle aspirates of breast carcinoma.

Recent preclinical and clinical data suggest that TP53 status and TP53 mutations may be important in determining tumour aggressiveness and therapy response. In this study we investigate the feasibility of a structural and quantitative analysis of TP53 on fine-needle aspiration (FNA) material obtaine...

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Detalles Bibliográficos
Autores principales: Lavarino, C., Corletto, V., Mezzelani, A., Della Torre, G., Bartoli, C., Riva, C., Pierotti, M. A., Rilke, F., Pilotti, S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151256/
https://www.ncbi.nlm.nih.gov/pubmed/9459157