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Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKC eta with MDR1, MRP and LRP gene expression.

A possible link between protein kinase C (PKC) and P-glycoprotein (P-gp)-mediated-multidrug resistance (MDR) was assumed from studies on MDR cell lines selected in vitro. The functional relevance of PKC for the MDR phenotype remains unclear, and the involvement of a particular PKC isozyme in clinica...

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Detalles Bibliográficos
Autores principales: Beck, J., Bohnet, B., Brügger, D., Bader, P., Dietl, J., Scheper, R. J., Kandolf, R., Liu, C., Niethammer, D., Gekeler, V.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151261/
https://www.ncbi.nlm.nih.gov/pubmed/9459150