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Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKC eta with MDR1, MRP and LRP gene expression.
A possible link between protein kinase C (PKC) and P-glycoprotein (P-gp)-mediated-multidrug resistance (MDR) was assumed from studies on MDR cell lines selected in vitro. The functional relevance of PKC for the MDR phenotype remains unclear, and the involvement of a particular PKC isozyme in clinica...
Autores principales: | Beck, J., Bohnet, B., Brügger, D., Bader, P., Dietl, J., Scheper, R. J., Kandolf, R., Liu, C., Niethammer, D., Gekeler, V. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151261/ https://www.ncbi.nlm.nih.gov/pubmed/9459150 |
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