99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein.

99mTc-sestamibi (99mTc-MIBI) is a substrate for the P-glycoprotein (P-gp) pump but it is not known whether it is a substrate for the multidrug resistance-associated protein (MRP) pump. Therefore, 99mTc-MIBI was evaluated in the GLC4 cell line and its doxorubicin-resistant MRP-, but not P-gp-, overex...

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Detalles Bibliográficos
Autores principales: Hendrikse, N. H., Franssen, E. J., van der Graaf, W. T., Meijer, C., Piers, D. A., Vaalburg, W., de Vries, E. G.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151293/
https://www.ncbi.nlm.nih.gov/pubmed/9472628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151293/
https://www.ncbi.nlm.nih.gov/pubmed/9472628

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