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99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein.
99mTc-sestamibi (99mTc-MIBI) is a substrate for the P-glycoprotein (P-gp) pump but it is not known whether it is a substrate for the multidrug resistance-associated protein (MRP) pump. Therefore, 99mTc-MIBI was evaluated in the GLC4 cell line and its doxorubicin-resistant MRP-, but not P-gp-, overex...
Autores principales: | Hendrikse, N. H., Franssen, E. J., van der Graaf, W. T., Meijer, C., Piers, D. A., Vaalburg, W., de Vries, E. G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151293/ https://www.ncbi.nlm.nih.gov/pubmed/9472628 |
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