Taxol-mediated augmentation of CD95 ligand-induced apoptosis of human malignant glioma cells: association with bcl-2 phosphorylation but neither activation of p53 nor G2/M cell cycle arrest.

The anti-tumour alkaloid taxol shows strong cytotoxic and antiproliferative activity in two human malignant glioma cell lines, T98G and LN-229. CD95 (Fas/APO-1) ligand is a novel cytotoxic cytokine of the tumour necrosis factor (TNF) family that exerts prominent antiglioma activity. At clinically re...

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Detalles Bibliográficos
Autores principales: Roth, W., Wagenknecht, B., Grimmel, C., Dichgans, J., Weller, M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151300/
https://www.ncbi.nlm.nih.gov/pubmed/9472635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151300/
https://www.ncbi.nlm.nih.gov/pubmed/9472635

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