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Access of Extracellular Cations to their Binding Sites in Na,K-ATPase: Role of the Second Extracellular Loop of the α Subunit

Na,K-ATPase, the main active transport system for monovalent cations in animal cells, is responsible for maintaining Na(+) and K(+) gradients across the plasma membrane. During its transport cycle it binds three cytoplasmic Na(+) ions and releases them on the extracellular side of the membrane, and...

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Detalles Bibliográficos
Autores principales: Capendeguy, Oihana, Chodanowski, Pierre, Michielin, Olivier, Horisberger, Jean-Daniel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151497/
https://www.ncbi.nlm.nih.gov/pubmed/16505152
http://dx.doi.org/10.1085/jgp.200509418