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Time-Dependent Block and Resurgent Tail Currents Induced by Mouse β4(154–167) Peptide in Cardiac Na(+) Channels

Resurgent tail Na(+) currents were first discovered in cerebellar Purkinje neurons. A recent study showed that a 14-mer fragment of a mouse β4 subunit, β4(154–167), acts as an intracellular open-channel blocker and elicits resurgent currents in Purkinje neurons (Grieco, T.M., J.D. Malhotra, C. Chen,...

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Detalles Bibliográficos
Autores principales: Wang, Ging Kuo, Edrich, Thomas, Wang, Sho-Ya
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151501/
https://www.ncbi.nlm.nih.gov/pubmed/16505148
http://dx.doi.org/10.1085/jgp.200509399