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Time-Dependent Block and Resurgent Tail Currents Induced by Mouse β4(154–167) Peptide in Cardiac Na(+) Channels
Resurgent tail Na(+) currents were first discovered in cerebellar Purkinje neurons. A recent study showed that a 14-mer fragment of a mouse β4 subunit, β4(154–167), acts as an intracellular open-channel blocker and elicits resurgent currents in Purkinje neurons (Grieco, T.M., J.D. Malhotra, C. Chen,...
Autores principales: | Wang, Ging Kuo, Edrich, Thomas, Wang, Sho-Ya |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151501/ https://www.ncbi.nlm.nih.gov/pubmed/16505148 http://dx.doi.org/10.1085/jgp.200509399 |
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