EGFR Kinase Regulates Volume-sensitive Chloride Current Elicited by Integrin Stretch via PI-3K and NADPH Oxidase in Ventricular Myocytes

Stretch of β1 integrins activates an outwardly rectifying, tamoxifen-sensitive Cl(−) current (Cl(−) SAC) via AT1 receptors, NADPH oxidase, and reactive oxygen species, and Cl(−) SAC resembles the volume-sensitive Cl(−) current (I(Cl,swell)). Epidermal growth factor receptor (EGFR) kinase undergoes t...

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Detalles Bibliográficos
Autores principales: Browe, David M., Baumgarten, Clive M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151502/
https://www.ncbi.nlm.nih.gov/pubmed/16505146
http://dx.doi.org/10.1085/jgp.200509366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151502/
https://www.ncbi.nlm.nih.gov/pubmed/16505146
http://dx.doi.org/10.1085/jgp.200509366

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