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EGFR Kinase Regulates Volume-sensitive Chloride Current Elicited by Integrin Stretch via PI-3K and NADPH Oxidase in Ventricular Myocytes
Stretch of β1 integrins activates an outwardly rectifying, tamoxifen-sensitive Cl(−) current (Cl(−) SAC) via AT1 receptors, NADPH oxidase, and reactive oxygen species, and Cl(−) SAC resembles the volume-sensitive Cl(−) current (I(Cl,swell)). Epidermal growth factor receptor (EGFR) kinase undergoes t...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151502/ https://www.ncbi.nlm.nih.gov/pubmed/16505146 http://dx.doi.org/10.1085/jgp.200509366 |