Cargando…

TRPM7 Channel Is Regulated by Magnesium Nucleotides via its Kinase Domain

TRPM7 is a Ca(2+)- and Mg(2+)-permeable cation channel that also contains a protein kinase domain. While there is general consensus that the channel is inhibited by free intracellular Mg(2+), the functional roles of intracellular levels of Mg·ATP and the kinase domain in regulating TRPM7 channel act...

Descripción completa

Detalles Bibliográficos
Autores principales: Demeuse, Philippe, Penner, Reinhold, Fleig, Andrea
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151514/
https://www.ncbi.nlm.nih.gov/pubmed/16533898
http://dx.doi.org/10.1085/jgp.200509410