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The Polyamine Binding Site in Inward Rectifier K(+) Channels

Strongly inwardly rectifying potassium channels exhibit potent and steeply voltage-dependent block by intracellular polyamines. To locate the polyamine binding site, we have examined the effects of polyamine blockade on the rate of MTSEA modification of cysteine residues strategically substituted in...

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Detalles Bibliográficos
Autores principales: Kurata, Harley T., Marton, Laurence J., Nichols, Colin G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151516/
https://www.ncbi.nlm.nih.gov/pubmed/16606689
http://dx.doi.org/10.1085/jgp.200509467