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Soluble Mediators, Not Cilia, Determine Airway Surface Liquid Volume in Normal and Cystic Fibrosis Superficial Airway Epithelia

A key aspect of the lung's innate defense system is the ability of the superficial epithelium to regulate airway surface liquid (ASL) volume to maintain a 7-μm periciliary liquid layer (PCL), which is required for cilia to beat and produce mucus flow. The mechanisms whereby airway epithelia reg...

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Detalles Bibliográficos
Autores principales: Tarran, Robert, Trout, Laura, Donaldson, Scott H., Boucher, Richard C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151517/
https://www.ncbi.nlm.nih.gov/pubmed/16636206
http://dx.doi.org/10.1085/jgp.200509468