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Functional Characterization of Homo- and Heteromeric Channel Kinases TRPM6 and TRPM7

TRPM6 and TRPM7 are two known channel kinases that play important roles in various physiological processes, including Mg(2+) homeostasis. Mutations in TRPM6 cause hereditary hypomagnesemia and secondary hypocalcemia (HSH). However, whether TRPM6 encodes functional channels is controversial. Here we...

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Detalles Bibliográficos
Autores principales: Li, Mingjiang, Jiang, Jianmin, Yue, Lixia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151519/
https://www.ncbi.nlm.nih.gov/pubmed/16636202
http://dx.doi.org/10.1085/jgp.200609502