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Membrane Stretch Slows the Concerted Step prior to Opening in a Kv Channel
In the simplest model of channel mechanosensitivity, expanded states are favored by stretch. We showed previously that stretch accelerates voltage-dependent activation and slow inactivation in a Kv channel, but whether these transitions involve expansions is unknown. Thus, while voltage-gated channe...
Autores principales: | Laitko, Ulrike, Juranka, Peter F., Morris, Catherine E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151533/ https://www.ncbi.nlm.nih.gov/pubmed/16735754 http://dx.doi.org/10.1085/jgp.200509394 |
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