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Statistical Limits to the Identification of Ion Channel Domains by Sequence Similarity
The study of ion channel function is constrained by the availability of structures for only a small number of channels. A commonly used bioinformatics technique is to assert, based on sequence similarity, that a domain within a channel of interest has the same structure as a reference domain for whi...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151544/ https://www.ncbi.nlm.nih.gov/pubmed/16735758 http://dx.doi.org/10.1085/jgp.200509419 |