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Statistical Limits to the Identification of Ion Channel Domains by Sequence Similarity

The study of ion channel function is constrained by the availability of structures for only a small number of channels. A commonly used bioinformatics technique is to assert, based on sequence similarity, that a domain within a channel of interest has the same structure as a reference domain for whi...

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Detalles Bibliográficos
Autores principales: Fodor, Anthony A., Aldrich, Richard W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151544/
https://www.ncbi.nlm.nih.gov/pubmed/16735758
http://dx.doi.org/10.1085/jgp.200509419

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