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Regulation of Maximal Open Probability Is a Separable Function of Ca(v)β Subunit in L-type Ca(2+) Channel, Dependent on NH(2) Terminus of α(1C) (Ca(v)1.2α)
β subunits (Ca(v)β) increase macroscopic currents of voltage-dependent Ca(2+) channels (VDCC) by increasing surface expression and modulating their gating, causing a leftward shift in conductance–voltage (G-V) curve and increasing the maximal open probability, P(o,max). In L-type Ca(v)1.2 channels,...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151559/ https://www.ncbi.nlm.nih.gov/pubmed/16801381 http://dx.doi.org/10.1085/jgp.200609485 |