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Regulation of Maximal Open Probability Is a Separable Function of Ca(v)β Subunit in L-type Ca(2+) Channel, Dependent on NH(2) Terminus of α(1C) (Ca(v)1.2α)

β subunits (Ca(v)β) increase macroscopic currents of voltage-dependent Ca(2+) channels (VDCC) by increasing surface expression and modulating their gating, causing a leftward shift in conductance–voltage (G-V) curve and increasing the maximal open probability, P(o,max). In L-type Ca(v)1.2 channels,...

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Detalles Bibliográficos
Autores principales:	Kanevsky, Nataly, Dascal, Nathan
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151559/ https://www.ncbi.nlm.nih.gov/pubmed/16801381 http://dx.doi.org/10.1085/jgp.200609485

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