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State-independent Block of BK Channels by an Intracellular Quaternary Ammonium

Intracellular blockade by quaternary ammonium (QA) molecules of many potassium channels is state dependent, where the requirement for channel opening is evidenced by a time-dependent component of block in the macroscopic record. Whether this is the case for Ca(2+)- and voltage-activated potassium (B...

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Detalles Bibliográficos
Autores principales: Wilkens, Christina M., Aldrich, Richard W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151567/
https://www.ncbi.nlm.nih.gov/pubmed/16940557
http://dx.doi.org/10.1085/jgp.200609579