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Single Cl(−) Channels Activated by Ca(2+) in Drosophila S2 Cells Are Mediated By Bestrophins
Mutations in human bestrophin-1 (VMD2) are genetically linked to several forms of retinal degeneration but the underlying mechanisms are unknown. Bestrophin-1 (hBest1) has been proposed to be a Cl(−) channel involved in ion and fluid transport by the retinal pigment epithelium (RPE). To date, howeve...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151570/ https://www.ncbi.nlm.nih.gov/pubmed/16940553 http://dx.doi.org/10.1085/jgp.200609581 |