Cargando…
Single Cl(−) Channels Activated by Ca(2+) in Drosophila S2 Cells Are Mediated By Bestrophins
Mutations in human bestrophin-1 (VMD2) are genetically linked to several forms of retinal degeneration but the underlying mechanisms are unknown. Bestrophin-1 (hBest1) has been proposed to be a Cl(−) channel involved in ion and fluid transport by the retinal pigment epithelium (RPE). To date, howeve...
Autores principales: | Chien, Li-Ting, Zhang, Zhi-Ren, Hartzell, H. Criss |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151570/ https://www.ncbi.nlm.nih.gov/pubmed/16940553 http://dx.doi.org/10.1085/jgp.200609581 |
Ejemplares similares
-
Drosophila Bestrophin-1 Currents Are Regulated by Phosphorylation via a CaMKII Dependent Mechanism
por: Duran, Charity, et al.
Publicado: (2013) -
Regulation of Bestrophin Cl Channels by Calcium: Role of the C Terminus
por: Xiao, Qinghuan, et al.
Publicado: (2008) -
Drosophila Bestrophin-1 Chloride Current Is Dually Regulated by Calcium and Cell Volume
por: Chien, Li-Ting, et al.
Publicado: (2007) -
Mouse Bestrophin-2 Is a Bona fide Cl(−) Channel: Identification of a Residue Important in Anion Binding and Conduction
por: Qu, Zhiqiang, et al.
Publicado: (2004) -
Anion Permeation in Ca(2+)-Activated Cl(−) Channels
por: Qu, Zhiqiang, et al.
Publicado: (2000)