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Intra- and Intersubunit Cooperativity in Activation of BK Channels by Ca(2+)
The activation of BK channels by Ca(2+) is highly cooperative, with small changes in intracellular Ca(2+) concentration having large effects on open probability (Po). Here we examine the mechanism of cooperative activation of BK channels by Ca(2+). Each of the four subunits of BK channels has a larg...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151572/ https://www.ncbi.nlm.nih.gov/pubmed/17001085 http://dx.doi.org/10.1085/jgp.200609486 |