Cyclic Nucleotide-gated Ion Channels in Rod Photoreceptors Are Protected from Retinoid Inhibition

In vertebrate rods, photoisomerization of the 11-cis retinal chromophore of rhodopsin to the all-trans conformation initiates a biochemical cascade that closes cGMP-gated channels and hyperpolarizes the cell. All-trans retinal is reduced to retinol and then removed to the pigment epithelium. The pig...

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Detalles Bibliográficos
Autores principales: He, Quanhua, Alexeev, Dmitriy, Estevez, Maureen E., McCabe, Sarah L., Calvert, Peter D., Ong, David E., Cornwall, M. Carter, Zimmerman, Anita L., Makino, Clint L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151575/
https://www.ncbi.nlm.nih.gov/pubmed/17001087
http://dx.doi.org/10.1085/jgp.200609619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151575/
https://www.ncbi.nlm.nih.gov/pubmed/17001087
http://dx.doi.org/10.1085/jgp.200609619

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