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Desensitization Contributes to the Synaptic Response of Gain-of-Function Mutants of the Muscle Nicotinic Receptor

Although the muscle nicotinic receptor (AChR) desensitizes almost completely in the steady presence of high concentrations of acetylcholine (ACh), it is well established that AChRs do not accumulate in desensitized states under normal physiological conditions of neurotransmitter release and clearanc...

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Detalles Bibliográficos
Autores principales: Elenes, Sergio, Ni, Ying, Cymes, Gisela D., Grosman, Claudio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151585/
https://www.ncbi.nlm.nih.gov/pubmed/17074980
http://dx.doi.org/10.1085/jgp.200609570