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Cooperative Gating between Single HCN Pacemaker Channels

HCN pacemaker channels (I(f), I(q), or I(h)) play a fundamental role in the physiology of many excitable cell types, including cardiac myocytes and central neurons. While cloned HCN channels have been studied extensively in macroscopic patch clamp experiments, their extremely small conductance has p...

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Detalles Bibliográficos
Autores principales: Dekker, John P., Yellen, Gary
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151591/
https://www.ncbi.nlm.nih.gov/pubmed/17043149
http://dx.doi.org/10.1085/jgp.200609599