A Cation–π Interaction between Extracellular TEA and an Aromatic Residue in Potassium Channels

Open-channel blockers such as tetraethylammonium (TEA) have a long history as probes of the permeation pathway of ion channels. High affinity blockade by extracellular TEA requires the presence of an aromatic amino acid at a position that sits at the external entrance of the permeation pathway (resi...

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Detalles Bibliográficos
Autores principales: Ahern, Christopher A., Eastwood, Amy L., Lester, Henry A., Dougherty, Dennis A., Horn, Richard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151593/
https://www.ncbi.nlm.nih.gov/pubmed/17130518
http://dx.doi.org/10.1085/jgp.200609654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151593/
https://www.ncbi.nlm.nih.gov/pubmed/17130518
http://dx.doi.org/10.1085/jgp.200609654

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