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A Cation–π Interaction between Extracellular TEA and an Aromatic Residue in Potassium Channels
Open-channel blockers such as tetraethylammonium (TEA) have a long history as probes of the permeation pathway of ion channels. High affinity blockade by extracellular TEA requires the presence of an aromatic amino acid at a position that sits at the external entrance of the permeation pathway (resi...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151593/ https://www.ncbi.nlm.nih.gov/pubmed/17130518 http://dx.doi.org/10.1085/jgp.200609654 |